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roxS [2017-04-28 10:33:02]
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roxS [2017-04-28 10:33:02]

small RNA, controls expression of ytdI, sucC-sucD, and yflS
Function
control of ytdI, sucC-sucD, and yflS expression
Product
trans-acting regulatory RNA
Essential
no
Synonyms
rsaE

Genomic Context

      
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Categories containing this gene/protein

  • Groups of genes → NcRNA → Regulatory RNAs

    • Expression and Regulation

    Operons

    Genes
    roxS

    Description

  • PubMed

    • Regulatory mechanism

  • ResD: transcriptional activation, PubMed, in ResD regulon
  • Rex: repression, PubMed, in Rex regulon

    • Regulation

  • induced by nitric oxide (NO) (ResD) PubMed
  • ResD: transcriptional activation PubMed
  • Rex: transcriptional repression PubMed

    • Additional information

  • the roxS RNA is degraded by the joined activities of RNase Y (initial endonucleolytic cleavage) and RNase J1 (processive degradation) PubMed
  • the roxS-ppnKB and roxS-sucC RNA duplexes form a cleavage site for RNase III PubMed
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    Biological materials

    Mutant

  • available in Ciaran Condon's lab PubMed

    • References

    Research papers

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    The RNA

    Catalyzed reaction/ biological activity

  • hybridizes to ytdI and sucD mRNAs to inhibit their translation and to destabilize them PubMed
  • binds the 5' end of the yflS mRNA to prevent its degradation by RNase J1 PubMed